Genetic programming outperformed multivariable logistic regression in diagnosing pulmonary embolism

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Genetic programming outperformed multivariable logistic regression in diagnosing pulmonary embolism.

OBJECTIVE Genetic programming is a search method that can be used to solve complex associations between large numbers of variables. It has been used, for example, for myoelectrical signal recognition, but its value for medical prediction as in diagnostic and prognostic settings, has not been documented. STUDY DESIGN AND SETTING We compared genetic programming and the commonly used logistic re...

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Diagnosing pulmonary embolism

No single non invasive test has sufficient diagnostic accuracy to be used alone for diagnosing or ruling out pulmonary embolism. Therefore, modern diagnostic strategies for pulmonary embolism rely on combinations of non invasive tests such as plasma D-dimer measurement, lower limb venous compression ultrasonography, ventilation-perfusion lung scan and/or spiral CT, the results of which should b...

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Diagnosing pulmonary embolism

A b st ra ct Pulmonary embolism (PE) is a common, treatable, highly lethal emergency, which despite advances in diagnostic testing, remains an under diagnosed killer. The mortality rate of diagnosed and treated pulmonary embolism ranges from 3-8%, but increases to about 30% in untreated pulmonary embolism. PE is a part of the spectrum of venousthromboembolic disease and most pulmonary emboli ha...

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Diagnosing pulmonary embolism.

Objective testing for pulmonary embolism is necessary, because clinical assessment alone is unreliable and the consequences of misdiagnosis are serious. No single test has ideal properties (100% sensitivity and specificity, no risk, low cost). Pulmonary angiography is regarded as the final arbiter but is ill suited for diagnosing a disease present in only a third of patients in whom it is suspe...

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Using Multiobjective Genetic Programming to Infer Logistic Polynomial Regression Models

In designing non-linear classifiers, there are important trade-offs to be made between predictive accuracy and model comprehensibility or complexity. We introduce the use of Genetic Programming to generate logistic polynomial models, a relatively comprehensible non-linear parametric model; describe an efficient twostage algorithm consisting of GP structure design and Quasi-Newton coefficient se...

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ژورنال

عنوان ژورنال: Journal of Clinical Epidemiology

سال: 2004

ISSN: 0895-4356

DOI: 10.1016/j.jclinepi.2003.10.011